| Autor: |
N Iu, Evdokimova, A S, Efimov, Iu V, Bezdrobnyĭ |
| Rok vydání: |
1985 |
| Předmět: |
|
| Zdroj: |
Voprosy meditsinskoi khimii. 31(2) |
| ISSN: |
0042-8809 |
| Popis: |
Binding of insulin to fatty cell plasmatic membranes in 10 patients with insulin-dependent diabetes mellitus exhibited high variability. The patients were divided into two groups based on the values of insulin binding. In the first group, comprising 3 patients, specific binding of insulin was below the values found in healthy persons; this phenomenon occurred only due to a decrease in content of insulin receptors. In the second group (7 patients) specific binding of insulin exceeded the values of controls; in this case an increase in affinity of the receptors was observed. These results suggest that insulin-dependent diabetes mellitus is characterized by high heterogeneity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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