| Autor: |
Valentin, Joubert, Matéo, Trébuchet, Mariana, Mikic, Virginie, Silvestre, Anne-Marie, Schiphorst, Denis, Loquet, Anaïs, Stemmelen, Virginie, Ladroue, Fabrice, Besacier, Serge, Akoka, Gérald S, Remaud |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Drug testing and analysisREFERENCES. 12(4) |
| ISSN: |
1942-7611 |
| Popis: |
In the battle against the illicit drugs market, methodologies have been developed by forensic laboratories to address the determination of the origin and dismantlement of the trafficking route for various target molecules such as heroin and cocaine. These drug profiling methods are not straightforward, especially when the target molecules are synthetic and very pure, resulting in poorly informative impurity profiles, e.g. new psychoactive substances and cutting agents. A tool based on the determination of intramolecular isotopic profiles has been developed to provide origin discrimination with a new way to profile seized cutting agents and heroin samples. Whereas stable isotope analyses by mass spectrometry give the bulk isotopic composition, nuclear magnetic resonance gives direct access to the position-specific isotope content at natural abundance. This report shows how both |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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