Prostaglandin E1 with phentolamine for the treatment of erectile dysfunction

Autor: W, Meinhardt, R B, de la Fuente, A A, Lycklama à Nijeholt, P, Vermeij, J, Zwartendijk
Rok vydání: 1996
Předmět:
Zdroj: International journal of impotence research. 8(1)
ISSN: 0955-9930
Popis: to evaluate the feasibility of a self-injection programme for impotence with a combination of 10 micrograms prostaglandine E1 (PGE1) and 0.5 mg phentolamine.follow-up at outpatients department with history taking, physical examination and questionnaires of 58 patients using this combination. Many patients could compare this drug combination with previously used drugs for intracavernous use.42 patients started regular use. After a follow-up of 14 months, 26 are still on the programme. Drug related problems encountered: 10 patients reported insufficient erectile response, five patients have had priapism, four patients experienced severe pain, one patient developed fibrosis.the combination of PGE1 and phentolamine is very effective. The complication rate is comparable with those reported from PGE1 alone and from papaverine with phentolamine.
Databáze: OpenAIRE