| Autor: |
Samuel J, MacKenzie, Juneyoung L, Yi, Amit, Singla, Thomas M, Russell, Blair, Calancie |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Musclenerve. 52(1) |
| ISSN: |
1097-4598 |
| Popis: |
The rat tail exhibits functional impairment after cauda equina injury. Our goal was to better understand the innervation and roles of muscles that control the tail.Adult rats received either: (1) ventral root injury; (2) caudales nerve injury; or (3) mapping of sacrococcygeal myotomes. Activation of small muscles within the tail itself (intrinsics) was compared with that of larger lumbosacral muscles acting on the tail (extrinsics). Behavioral testing of tail movement was done 1 week later.Rats that received ventral root injury exhibited multiple behavioral deficits, whereas rats with injury to caudales nerves maintained more fully preserved tail movement. Mapping studies revealed much broader overlap of myotomes for extrinsic muscles.Extrinsic tail muscles play a greater role in tail movement in the rat than their intrinsic counterparts and are innervated by multiple neurological segments. These findings have major implications for future research on cauda equina injury. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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