[Activity of antioxidant enzymes in enterocytes of the small intestine and blood cells after ionizing irradiation and administration of vitamin E in rats]

Autor:	H Ia, Kleveta, L S, Starykovych, Ia P, Chaĭka, T V, Vyhovs'ka, H M, Pauk, L O, Datsiuk, O V, Trykulenko, M M, Velykyĭ, H V, Donchenko, I V, Kuz'menko
Rok vydání:	2004
Předmět:	Glutathione Peroxidase Lipid Peroxides Erythrocytes Superoxide Dismutase X-Rays Bone Marrow Cells Dose-Response Relationship Radiation Catalase Radiation Dosage Antioxidants Rats Radiation Injuries Experimental Enterocytes Glutathione Reductase Intestine Small Animals Vitamin E
Zdroj:	Ukrains'kyi biokhimichnyi zhurnal (1999 ). 75(6)
Popis:	The long-term influence of low X-ray irradiation increases lipid peroxidation (LP) in radiosensitive (bone marrow, enterocytes of small intenstine) and in relatively radioresistant blood cells (erythrocytes). The activation of antioxidant system enzymes in observed cells does not decrease LP intensity. We concluded that additional administration of alpha-tocopherol provided the decrease of the first and end products of LP in the observed tissues mostly in the beginning of the experiment. Antioxidant effect of the preparation is more significant in cells with high proliferative activity but normal activity of enzymes was not determined.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::e8e5224fc155aaf27aa57dffa8b4488f https://pubmed.ncbi.nlm.nih.gov/15143523 Zobrazit plný text záznamu