SlyD Accelerates
| Autor: | Abhigyan, Sengupta, Lorenz E, Rognoni, Ulrich, Merkel, Gabriel, Žoldák, Matthias, Rief |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | The journal of physical chemistry. B. 125(31) |
| ISSN: | 1520-5207 |
| Popis: | Prolyl isomerization is recognized as one of the key regulatory mechanisms, which plays a crucial role in cell signaling, ion channel gating, phage virus infection, and molecular timing. This isomerization is usually slow but often accelerated by an enzyme, called peptidyl-prolyl isomerase (PPIase). In the current project, we investigate using single-molecule force spectroscopy (SMFS) the impact of a bacterial PPIase, SlyD, on the |
| Databáze: | OpenAIRE |
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