[Clinical and epidemiological features of tuberculosis ostitis in BCG-vaccinated children]

Autor: N G, Kamaeva, Iu P, Chugaev, L M, Grinberg, N A, Anisimova, T V, Golubeva, E Iu, Kamaev
Rok vydání: 2009
Předmět:
Zdroj: Problemy tuberkuleza i boleznei legkikh. (1)
ISSN: 1728-2993
Popis: There has been a drastic increase in the incidence of ostitis in children since 2001. Comparison of current tuberculous ostitis (n = 70) and primary pulmonary tuberculosis (n = 60) in infants revealed significant clinical and epidemiological differences. Molecular genetic methods identified BCG M. bovis strain DNA in 13 (46.4%) intraoperative samples and 4 samples of obtained cultures from bone destruction foci. Isolation of BCG cultures and/or verification of BCG M. ovis DNA from the bone lesion focus by polymerase chain reaction is a significant criterion for verification of the BCG etiology of ostitis having a morphological pattern of productive necrotic tuberculosis in children.
Databáze: OpenAIRE