Amniotic fluid OD 650 as a rapid indicator of fetal pulmonary maturity

Autor: G, Matile, H, Grundy, H, Kilbride, R, O'Kell, C, Dannar
Rok vydání: 1985
Předmět:
Zdroj: The Journal of reproductive medicine. 30(3)
ISSN: 0024-7758
Popis: Amniotic fluid OD 650 (optical density at 650 nm) greater than 0.15 has been associated with mature L/S ratios. This study compared OD 650 with the L/S ratio on 235 uncontaminated amniotic fluid specimens. Follow-up was obtained on 138 neonates delivered within 72 hours of amniocentesis. Of 124 amniotic fluid specimens with OD 650 greater than 0.15, 109 had mature L/S ratios. Only 3 of 96 neonates with OD 650 greater than 0.15 developed respiratory distress syndrome; 8 of 42 neonates with OD 650 values less than 0.15 developed it. The false-positive rate (2.1%) compared favorably with that of the L/S ratio (2.9%). A higher false-negative rate (24.6%) decreased the efficiency of OD 650 as an indicator of fetal pulmonary maturity. An OD 650 greater than 0.15 appears to be a rapid, reliable indicator of fetal lung maturity.
Databáze: OpenAIRE