Microsatellite instability testing
| Autor: | Y R, Parc, K C, Halling |
|---|---|
| Rok vydání: | 2011 |
| Zdroj: | Methods in molecular medicine. 50 |
| ISSN: | 1543-1894 |
| Popis: | Microsatellites are tandem repeats of simple sequences that occur abundantly and are randomly interspersed throughout the human genome. They typically consist of 10-50 copies of 1-6 bp motifs, and are characterized by a high degree of polymorphism. Despite the variability observed among individuals, microsatellite are replicated faithfully at each cell division in normal germline and somatic cells (1). |
| Databáze: | OpenAIRE |
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