| Autor: |
M O, Samoĭlov, E V, Lazarevich, D G, Semenov, A A, Mokrushin, E I, Tiul'kova, D Iu, Romanovskiĭ, E A, Miliakova, K N, Dudkin |
| Rok vydání: |
2001 |
| Předmět: |
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| Zdroj: |
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 87(6) |
| ISSN: |
0869-8139 |
| Popis: |
A preventive short-term hypoxia (preconditioning) increases neuronal resistance against subsequent strong hypoxic effects. Literature review and authors' own data on molecular-cellular mechanisms of the hypoxic preconditioning, are presented. Participation of intracellular signal transduction, genome, stress-proteins, and neuromodulating peptides in this process, is discussed. The role of glutamatergic as well as calcium and phosphoinositide regulatory systems and neuromodulating factors as the components of a "volume" signal transmission are analyzed in hypoxic precondition-associated induction of functional tolerance mechanisms against acute harmful effects in neurones of olfactory slices. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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