| Autor: |
Okkes, Yilmaz, Yasemin, Ersan, Ayse, Dilek Ozsahin, Ali, Ihsan Ozturk, Yusuf, Ozkan |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Iranian Journal of Basic Medical Sciences |
| ISSN: |
2008-3866 |
| Popis: |
Objective(s): Our objective was to evaluate the effects of a triple antioxidant combination [α-tocopherol (AT), ascorbic acid (AA) and α-lipoic acid (LA); AT+AA+LA] on the cholesterol and glutathione levels, and the fatty acid composition of liver and muscle tissues in diabetic rats. Materials and Methods: Forty-three Wistar rats were randomly divided into five groups. The first group was used as a control. The second, third and fourth groups received STZ (45 mg/kg) in citrate buffer. The fourth and fifth groups were injected with intraperitoneal (IP) 50 mg/kg DL-AT and 50 mg /kg DL-LA four times per week and received water-soluble vitamin C (50 mg/kg) in their drinking water for a period of six weeks. Results: Liver cholesterol levels in the AT+AA+LA group were lower than the control (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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