Evaluation of salvage surgery in heavily irradiated cancer of the buccal mucosa

Autor:	T, Cherian, P, Sebastian, M I, Ahamed, K L, Jayakumar, P, Sivaramakrishnan, G, Jeevy, R, Sankaranarayanan, M K, Nair
Rok vydání:	1991
Předmět:	Adult Aged 80 and over Male Middle Aged Combined Modality Therapy Survival Rate Postoperative Complications Lymphatic Metastasis Carcinoma Squamous Cell Humans Female Mouth Neoplasms Neoplasm Recurrence Local Aged Follow-Up Studies Neoplasm Staging
Zdroj:	Cancer. 68(2)
ISSN:	0008-543X
Popis:	This report describes the authors' experience with salvage surgery in 78 patients with carcinoma of the buccal mucosa who failed after high-dose radical radiation therapy at Regional Cancer Centre, Trivandrum, India. Forty-four patients (56%) required a hemimandibulectomy for adequate tumor clearance. Fifty-four patients (69%) required a primary reconstructive procedure for wound closure. Follow-up periods ranged from 28 months to 63 months (median follow-up, 41 months). Thirteen patients (17%) developed nonfatal postoperative complications. Thirty-one patients recurred after surgery, five of whom were again salvaged by further surgery. Overall, the recurrence rate was 36%. Most of the recurrences (26/31) were at the primary site. The overall 5-year actuarial disease-free survival after salvage surgery was 59.7%. T stage of the recurrent tumor and its skin infiltration emerged as factors which significantly influenced disease-free survival (P less than 0.05).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::e75d435a955efe9e1dcaf5a91e7456c0 https://pubmed.ncbi.nlm.nih.gov/2070328 Zobrazit plný text záznamu Plný text