| Autor: |
A V, Ivashchenko, M G, Kadieva, D V, Kravchenko, Ia V, Lavrovskiĭ, O D, Mit'kin, R M, Salimov, Iu A, Fedotov |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Eksperimental'naia i klinicheskaia farmakologiia. 73(3) |
| ISSN: |
0869-2092 |
| Popis: |
The influence of ethyl-3-(8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-gamma-carboline-5-yl)propionate dihydrochloride belonging to the class of gamma-carbolines on the allergic reactions (inflammation and systemic anaphylaxis) has been studied on laboratory animals. It was established that the given substance administered in a dose of 5 - 20 mg/kg exhibits a pronounced antiallergic action. Unlike many other antihistamine drugs, this gamma-carboline derivative probably does not produce sedative effect. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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