| Autor: |
R, Asero, E, Bertetti, L, Origgi, P, Riboldi, C, Zanussi |
| Rok vydání: |
1990 |
| Předmět: |
|
| Zdroj: |
Journal of clinicallaboratory immunology. 31(3) |
| ISSN: |
0141-2760 |
| Popis: |
The relationships between autoantibodies to soluble cellular antigens and clinical features in systemic lupus erythematosus (SLE) were investigated in a large clinical-serological study. The absence of these precipitins in serum was associated with a low prevalence of vasculitis and membranous nephropathy (MGN). Other significant findings were the associations between nRNP antibody and Raynaud's phenomenon and MGN, SSB antibody and sicca complex, PCNA antibody and a young age at onset, and Bu antibody and an old age at onset. However, the most impressive findings were in DA1-positive patients which showed a unique prevalence of photosensitive skin lesions, lymphoadenopathy and hepatosplenomegaly. The present study confirms the usefulness of antibodies to soluble cellular antigens in the classification of patients with SLE. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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