Aortopulmonary collateral flow quantification by MR at rest and during continuous submaximal exercise in patients with total cavopulmonary connection

Autor: Naira, Mkrtchyan, Yvonne, Frank, Eva, Steinlechner, Lenika, Calavrezos, Christian, Meierhofer, Alfred, Hager, Stefan, Martinoff, Peter, Ewert, Heiko, Stern
Rok vydání: 2017
Předmět:
Zdroj: Journal of magnetic resonance imaging : JMRI. 47(6)
ISSN: 1522-2586
Popis: Aortopulmonary collateral flow is considered to have significant impact on the outcome of patients with single ventricle circulation and total cavopulmonary connection (TCPC). There is little information on collateral flow during exercise.To quantify aortopulmonary collateral flow at rest and during continuous submaximal exercise in clinical patients doing well with TCPC.Prospective, case controlled.Thirteen patients with TCPC (17 (11-37) years) and 13 age and sex-matched healthy controls (18 (11-38) years).1.5T; free breathing; phase sensitive gradient echo sequence.Blood flow in the ascending and descending aorta and superior vena cava were measured at rest and during continuous submaximal physical exercise in patients and controls. Systemic blood flow (QMann-Whitney U-test and Wilcoxon test for comparison between groups and between rest and exercise.Absolute collateral flow in TCPC patients at rest was 0.4 l/min/mClinical patients doing well with TCPC have significant aortopulmonary collateral flow at rest (14% of Q2 Technical Efficacy: Stage 3 J. Magn. Reson. Imaging 2018;47:1509-1516.
Databáze: OpenAIRE