Metabolic profiling of ob/ob mouse fatty liver using HR-MAS

Autor:	Mikheil, Gogiashvili, Karolina, Edlund, Kathrin, Gianmoena, Rosemarie, Marchan, Alexander, Brik, Jan T, Andersson, Jörg, Lambert, Katrin, Madjar, Birte, Hellwig, Jörg, Rahnenführer, Jan G, Hengstler, Roland, Hergenröder, Cristina, Cadenas
Rok vydání:	2016
Předmět:	Leptin Male Proton Magnetic Resonance Spectroscopy Betaine Fatty Liver Mice Liver Metabolome Animals Metabolomics Lactic Acid Transcriptome Gene Deletion Metabolic Networks and Pathways
Zdroj:	Analytical and bioanalytical chemistry. 409(6)
ISSN:	1618-2650
Popis:	Metabolic perturbations resulting from excessive hepatic fat accumulation are poorly understood. Thus, in this study, leptin-deficient ob/ob mice, a mouse model of fatty liver disease, were used to investigate metabolic alterations in more detail. Metabolites were quantified in intact liver tissues of ob/ob (n = 8) and control (n = 8) mice using high-resolution magic angle spinning (HR-MAS)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::e610472415664acb895435e2bee02e24 https://pubmed.ncbi.nlm.nih.gov/27896396 Zobrazit plný text záznamu Full text from SpringerLink