Fetal megacystis: prediction of spontaneous resolution and outcome

Autor: F, Fontanella, L, Duin, P N, Adama van Scheltema, T E, Cohen-Overbeek, E, Pajkrt, M, Bekker, C, Willekes, C J, Bax, C M, Bilardo
Rok vydání: 2016
Předmět:
Zdroj: Ultrasound in obstetricsgynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 50(4)
ISSN: 1469-0705
Popis: To investigate the natural history of fetal megacystis from diagnosis in utero to postnatal outcome, and to identify prognostic indicators of spontaneous resolution and postnatal outcome after resolution.This was a national retrospective cohort study. Fetal megacystis was defined in the first trimester as a longitudinal bladder diameter (LBD) ≥ 7 mm, and in the second and third trimesters as an enlarged bladder failing to empty during the entire extended ultrasound examination. LBD and gestational age (GA) at resolution were investigated with respect to likelihood of resolution and postnatal outcome, respectively. Sensitivity, specificity and area under the receiver-operating characteristics curve (AUC) were calculated.In total, 284 cases of fetal megacystis (93 early megacystis, identified before the 18In fetal megacystis, LBD and GA at regression can be used as predictors of resolution and outcome, respectively. These parameters could help in fine-tuning the prognosis and optimizing the frequency of follow-up scans. Copyright © 2017 ISUOG. Published by John WileySons Ltd.
Databáze: OpenAIRE