| Autor: |
S, Woldesenbet, R, Garcia, N, Igbo, J, Leake, S K, Lewis, G R, Newton |
| Rok vydání: |
2004 |
| Předmět: |
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| Zdroj: |
American journal of reproductive immunology (New York, N.Y. : 1989). 52(1) |
| ISSN: |
1046-7408 |
| Popis: |
The goal of this study was to determine if caprine conceptuses express lectin-like receptors for endometrial H-type 1 (HT1) antigen.Conceptus tissues were collected during the apposition, adhesion and attachment phases of placentation and evaluated using immunofluorescence microscopy.Conceptus staining for the trisaccharide lacto-N-fucopentaose-1 was strong and uniform during apposition of fetal and maternal tissues but changed by day 25 of pregnancy when large aggregates of intense staining were observed. Monoclonal antibodies to galectin-3 did not stain conceptus tissue during the apposition phase but intense punctate staining was observed after day 25. Strong uniform staining for Lewis Y antigen was detected only on day 17 of pregnancy.Conceptus tissue expresses potential receptors for endometrial HT1 antigen. Carbohydrate-lectin interactions may facilitate attachment of the apical surfaces of uterine epithelial cells and trophectoderm during the early stages of placentation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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