Are electrophysiological criteria useful in distinguishing childhood demyelinating neuropathies?

Autor:	Anna, Potulska-Chromik, Barbara, Ryniewicz, Karolina, Aragon-Gawinska, Dagmara, Kabzinska, Andrzej, Seroka, Marta, Lipowska, Anna M, Kaminska, Anna, Kostera-Pruszczyk
Rok vydání:	2015
Předmět:	Male Adolescent Electrodiagnosis Neural Conduction Diagnosis Differential Electrophysiology Polyradiculoneuropathy Chronic Inflammatory Demyelinating Charcot-Marie-Tooth Disease Child Preschool Humans Female Child Hereditary Sensory and Motor Neuropathy Retrospective Studies
Zdroj:	Journal of the peripheral nervous system : JPNS. 21(1)
ISSN:	1529-8027
Popis:	Childhood chronic inflammatory demyelinating polyneuropathy (CIDP) needs to be differentiated from hereditary neuropathy. We aimed to validate existing CIDP nerve conduction study (NCS) criteria in a group of children with demyelinating neuropathies of chronic or subacute onset. Retrospective analysis of clinical and NCS results in 18 children with CIDP, 7 with hereditary neuropathy with pressure palsy (HNPP), and 24 with Charcot-Marie-Tooth 1a (CMT1a). AAN and EFNS electrodiagnostic CIDP criteria were fulfilled in 17 of 18 CIDP, 3 of 7 HNPP, and 23 of 24 CMT1a patients. A distal compound muscle action potential (dCMAP) of9 ms was observed in 14 of 18 CIDP patients but not in any patients with HNPP. Abnormal median/normal sural SNAP (AMNS) and a 10 m/s difference between conduction velocities (CV) of two corresponding nerves were not observed in any CMT1a patients. NCS in CMT1a, HNPP, and CIDP reflect demyelination. dCMAP duration, sensory AMNS, and a 10 m/s CV difference parameter are most useful in the differential diagnosis of pediatric CIDP.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::e5ce9c60b294d451c8aa60df847e744e https://pubmed.ncbi.nlm.nih.gov/27251939 Zobrazit plný text záznamu Plný text