Herpes simplex virus life cycle and the design of viral vectors

Autor: D S, Latchman
Rok vydání: 2011
Zdroj: Methods in molecular biology (Clifton, N.J.). 8
ISSN: 1064-3745
Popis: Herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2) are doublestranded DNA viruses with a genome size of 152 kbp. The genome consists of two unique regions, U(L) (long) and U(s) (short), flanked by repeated sequences (Fig. 1; for review, see ref. 1). The two viruses are closely related, and both infect humans, producing mucocutaneous sores that are predominantly facial in the case of HSV-1 and genital in the case of HSV-2.
Databáze: OpenAIRE