Methemoglobinemie consecutive a l'abus de gel de lidocaïne visqueuse

Autor:	C, Lacroix, M, Peureux, M, Borel, J, Goulle
Rok vydání:	2014
Zdroj:	Acta clinica Belgica. 57
ISSN:	1784-3286
Popis:	Lidocaine use may lead to methemoglobinemia. Lidocaine is clinically widely used as an anaesthesic drug, however its toxic effect is rare. We report a high methemoglobinemia level of 31.1 % following repeated Xylocaine® gel oral applications. New metabolic pathways of lidocaine have been reported leading to dimethylphenylhydroxylamine in humans. This metabolism is very similar to the aniline derivative ones, and may explain lidocaine methemoglobinemia effect.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::e52c83ad1e5fcdc28ea37e8a1e647e2f https://pubmed.ncbi.nlm.nih.gov/24862528 Zobrazit plný text záznamu