| Autor: |
Peng, Hu, Tong-Hua, Yang, Ren-Bin, Zhao, Ke-Qian, Shi, Yan-Mei, Yang, Xun, Lai |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Zhongguo shi yan xue ye xue za zhi. 26(5) |
| ISSN: |
1009-2137 |
| Popis: |
To investigate the efficacy of hematopoietic stem cells cryopreserved by ladder-style freezing from low temperature refrigerator to liquid nitrogen in treatment of hematological malignancies, and to analyze the survival condition of patients after hematopoietic stem cell transplantation.The coyoprotectant formed by 3% hydroxyethyl starch, 4% albumin and 5% dimethyl sulfoxide (DMSO) was need for cryopreservation of hematopoietic stem cells,which were first placed in -80One case failed in implantation due to intracranial hemorrhage and the other 97 cases all succeeded in hematopoietic reconstitution. The average time needed for neutrophil count ≥0.5×10ladder-style freezing from low temperature refrigerator to liquid nitrogen can reach the same clinical transplantation effect with traditional programmed cooling freezing method in autologous hematopoietic stem cells transplantation. moreover the incidence of complications after transpeantatim does not show increase. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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