| Autor: |
C E, Lewis, A M, Fry, J R, Hermann, D, Siev, D M, Dusek, D M, Gatewood |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Developments in biologicals. 134 |
| ISSN: |
1424-6074 |
| Popis: |
Vaccination of domestic animals against rabies creates a critical barrier between wildlife reservoirs and the human population. Ensuring these vaccines are potent and effective is paramount in preventing human exposure to this deadly and costly disease. The National Institutes of Health (NIH) test is, at present, the most widely used and internationally recommended potency assay for batch testing inactivated rabies vaccines. This test has numerous inherent limitations and disadvantages, including a lack of precision. The NIH test requires a large number of animals and involves unrelieved pain and suffering. A relevant in vitro assay should provide a more accurate, reproducible, rapid, safe, and humane rabies vaccine potency test. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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