Immunohistochemical detection of hepatitis C virus related C100-3 and core antigens in formalin-fixed liver tissue

Autor: A, Chamlian, L, Benkoël, J, Sahel, A, Cherid, J, Brisse, J F, Ikoli, R, Lambert, X, De Lamballerie
Rok vydání: 1996
Předmět:
Zdroj: Cellular and molecular biology (Noisy-le-Grand, France). 42(4)
ISSN: 0145-5680
Popis: HCV C100-3 non-structural and core proteins have been detected by immunohistochemical methods on paraffin-embedded tissue sections using monoclonal antibodies in 22 cases of chronic hepatitis C. C100-3 protein was detected in cytoplasm and nuclei of hepatocytes whereas core protein was only detected in nuclei. The specificity of the nuclear localization of HCV antigens was discussed in relation to cross-reactivity of the anti core antibody with host-derived GOR antigen.
Databáze: OpenAIRE