Gastric and jejunal histopathological changes in patients undergoing bariatric surgery

Autor: Rosemary Simões Nomelini, Rodrigues, Élia Cláudia de Souza, Almeida, Júverson Alves, Terra, Lucinda Calheiros, Guimarães, Ana Cristina da Rocha, Duque, Renata Margarida, Etchebehere
Rok vydání: 2016
Předmět:
Zdroj: Arquivos de gastroenterologia. 54(1)
ISSN: 1678-4219
Popis: Morbid obesity is a multifactorial disease that is increasingly treated by surgery.- To evaluate gastric histopathological changes in obese, and to compare with patients who underwent gastrojejunal bypass and the jejunal mucosa after the surgery.- This is an observational study performed at a tertiary public hospital, evaluating endoscopic biopsies from 36 preoperative patients and 35 postoperative.- In the preoperative group, 80.6% had chronic gastritis, which was active in 38.9% (77.1% and 20.1%, respectively, in the postoperative). The postoperative group had a significant reduction in Helicobacter pylori infection (P=0.0001). A longer length of the gastric stump and a time since surgery of more than two years were associated with Helicobacter pylori infection. The jejunal mucosa was normal in 91.4% and showed slight nonspecific chronic inflammation in 8.6%.- There was a reduction in the incidence of Helicobacter pylori infection in the postoperative group. A longer length of the gastric stump and longer time elapsed since surgery were associated with Helicobacter pylori infection. The jejunal mucosa was considered normal in an absolute majority of patients.
Databáze: OpenAIRE