Ultra-sensitive

Autor: Julie A, Vendrell, Julien, Mazieres, Romain, Senal, Isabelle, Rouquette, Xavier, Quantin, Jean-Louis, Pujol, Benoit, Roch, Abdelali, Bouidioua, Sylvain, Godreuil, Etienne, Coyaud, Pierre, Brousset, Jérôme, Solassol
Rok vydání: 2018
Předmět:
Zdroj: Clinical cancer research : an official journal of the American Association for Cancer Research. 25(14)
ISSN: 1557-3265
Popis: The detection of preexistingA total of 179 tumor samples from patients treated or not with a first-generation tyrosine kinase inhibitor (TKI) was analyzed. The presence of ultra-low levels of preexisting EGFRWith a ddPCR linear performance of 0.999 and an analytical sensitivity of approximately 0.001%, we observed a 66% (99/150) overall incidence of ultra-lowWe demonstrate that the detection of the ultra-low
Databáze: OpenAIRE