Salsolinol Protects SH-SY5Y Cells Against MPP

Autor: Magdalena, Kurnik-Łucka, Gniewomir, Latacz, Joanna, Goryl, Veronika, Aleksandrovych, Krzysztof, Gil
Rok vydání: 2022
Zdroj: Neurochemical research.
ISSN: 1573-6903
Popis: A dopamine derivative, 1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, known as salsolinol (SAL), has increasingly gained attention since its first detection in the urine of Parkinson's disease patients treated with levodopa, and has been proposed as a possible neurotoxic contributor to the disease. Yet, so far, the neurobiological role of SAL remains unclear. Thus, the main aims of our study were to compare the neurotoxic potential of SAL with MPP
Databáze: OpenAIRE