Nicotinamide-independent asymmetric bioreduction of C 000000000000 000000000000 000000000000 111111111111 000000000000 111111111111 000000000000 000000000000 000000000000 C-bonds via disproportionation of enones catalyzed by enoate reductases
Autor: | Stueckler, Clemens, Reiter, Tamara C., Baudendistel, Nina, Faber, Kurt |
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Jazyk: | angličtina |
Rok vydání: | 2010 |
Předmět: | |
Zdroj: | Tetrahedron |
ISSN: | 0040-4020 |
Popis: | The asymmetric bioreduction of activated CC-bonds catalyzed by a single flavoprotein was achieved via direct hydrogen transfer from a sacrificial 2-enone or 1,4-dione as hydrogen donor without requirement of a nicotinamide cofactor. Due to its simplicity, this system has clear advantages over conventional FAD-recycling systems. Graphical abstract |
Databáze: | OpenAIRE |
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