Nicotinamide-independent asymmetric bioreduction of C 000000000000 000000000000 000000000000 111111111111 000000000000 111111111111 000000000000 000000000000 000000000000 C-bonds via disproportionation of enones catalyzed by enoate reductases

Autor:	Stueckler, Clemens, Reiter, Tamara C., Baudendistel, Nina, Faber, Kurt
Jazyk:	angličtina
Rok vydání:	2010
Předmět:	Flavin Enoate reductase Article Biotransformation Disproportionation Cofactor recycling
Zdroj:	Tetrahedron
ISSN:	0040-4020
Popis:	The asymmetric bioreduction of activated CC-bonds catalyzed by a single flavoprotein was achieved via direct hydrogen transfer from a sacrificial 2-enone or 1,4-dione as hydrogen donor without requirement of a nicotinamide cofactor. Due to its simplicity, this system has clear advantages over conventional FAD-recycling systems. Graphical abstract
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::e42d474bbb54acab3072ee8a13cc724e http://europepmc.org/articles/PMC3007678 Zobrazit plný text záznamu Full Text from ScienceDirect