[Pharmacokinetic and clinical research of a new phenyl ester of carbecinillin: carfecillin]

Autor:	N, Sachelariu, M L, Soranzo, G, Bosio, M, Sattinger, C, Bramato, B, Salassa
Rok vydání:	1979
Předmět:	Adult Carfecillin Male Clinical Trials as Topic Adolescent Middle Aged Staphylococcal Infections Carbenicillin Streptococcal Infections Cystitis Urinary Tract Infections Drug Evaluation Humans Female Pseudomonas Infections Proteus Infections Escherichia coli Infections Aged
Zdroj:	Minerva medica. 70(32)
ISSN:	0026-4806
Popis:	Following a review of the latest methods of treating infections of the urinary ways, the pharmacokinetic and clinical results of a new antibiotic, Carfecillin, are reported. The examination was carried out on a total of 10 volunteers. The substance showed good serum levels and fair renal excretion with both the 250 mg and the 500 mg p.o. doses. The clinical study was carried out on a double blind basis versus a standard reference (indanyl ester of carbenicillin) in 26 patients and showed the electivity of the antibiotic in the oral treatment of urinary infections under well tolerated conditions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::e41487f7726ec55a6b079f633ac4b9b8 https://pubmed.ncbi.nlm.nih.gov/379704 Zobrazit plný text záznamu