[Physico-chemical properties of 7-aminodesacetoxycephalosporanic acid]

Autor: P S, Nys, E V, Kol'tsova, N N, Shellenberg, E M, Savitskaia, M M, Levitov
Rok vydání: 1976
Předmět:
Zdroj: Antibiotiki. 21(5)
ISSN: 0003-5637
Popis: 7-Aminodesacetoxycephalosporanic acid (7-ADCA) of 99 per cent purity was prepared by enzymatic hydrolysis of 7-phenylacetamidodesacetoxycephalosporanic acid. Its isoelecti point was determined by the electrophoretic method. Potentiometric titration of zwitterion of 7-ADCA was performed and the constants of its ionization were calculated. Minimum solubility of 7-ADCA zwitterion was determined and the curve of 7-ADCA solubility at wide pH ranges was estimated. Equilibrium of 3 forms of 7-ADCA was estimated.
Databáze: OpenAIRE