Vacuum-induced Suction Stimulates Increased Numbers of Blood Vessels in Healthy Dog Gingiva

Autor: Oksana V, Budinskaya, Elias D, Kontogiorgos, Meredith, Brownlee, Jennifer S, Lee, Roman A, Budinskiy, Paul C, Dechow, John M, Wright, Kathy K H, Svoboda, Lynne A, Opperman
Rok vydání: 2015
Zdroj: Wounds : a compendium of clinical research and practice. 24(4)
ISSN: 1044-7946
Popis: This study was designed to determine if vacuum-induced suction increased the number of blood vessels in healthy dog gingiva as a prelude to future studies testing vacuum therapy for improving local blood supply and controlling periodontal disease.The buccal gingiva of five dogs was treated with subatmospheric pressure for 5 days, with untreated tissues acting as controls. Biopsies were analyzed for vascular endothelial growth factors (VEGF) and blood vessels were counted.VEGF and vessel numbers were elevated in treatment groups compared to controls (P0.05).A single daily application of subatmospheric pressure might be beneficial for healing damaged or diseased gingival tissues. .
Databáze: OpenAIRE