[Regulation of peroxidation of mitochondrial membrane lipids initiated by Fe2+ ions by antoxidants of the 1,4-dihydropyridine series in experiments in vitro]

Autor:	G Ia, Dubur, A Kh, Velena, V M, Gukasov, Iu A, Vladimirov
Rok vydání:	1976
Předmět:	Male Chemistry Membrane Lipids Chemical Phenomena Histocytochemistry Pyridines Iron Animals Mitochondria Liver In Vitro Techniques Antioxidants Rats
Zdroj:	Voprosy meditsinskoi khimii. 22(5)
ISSN:	0042-8809
Popis:	Effect of antioxidants on the rate of free radical peroxidation was studied in mitochondria in presence of Fe2+. For this purpose derivatives of 1,4-dihydroxypyridine, their heteroaromatic analogues, NAD-H+ and butyl hydroxytoluene (35 substances) were tested in the system by chemoluminescence. Several 1,4-dihydroxypyridine derivatives were found to be effective reagents in the system and could be compared by the activity with the recognized synthetic antioxidant butyl hydroxytoluene.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::e392af1bf3ca0827aafcd94e03b09d33 https://pubmed.ncbi.nlm.nih.gov/1014479 Zobrazit plný text záznamu