| Autor: |
T V, Astakhova, M N, Lobanov, I V, Poverennaia, M A, Roĭtberg, V V, Iakovlev |
| Rok vydání: |
2012 |
| Předmět: |
|
| Zdroj: |
Biofizika. 57(2) |
| ISSN: |
0006-3029 |
| Popis: |
The verification of the PREFAB database containing golden standard protein alignments was performed. It has revealed a significant number of differences between the sequences from PREFAB and PDB databases. It was shown that compared to the sequences given in the PDB database 575 alignments refered to a sequence with a gap; such alignments were excluded. Furthermore, compared to the PDB-sequences a single substitute or the insertions were found for 440 aminoacid sequences from PREFAB database; these sequences were edited. SCOP domain analysis has shown that only 502 alignments in the resulting set contain the sequences from the same family. Finally, eliminating duplicates, we have created a new golden standard alignment database PREFAB-P based on PREFAB; the PREFAB-P database contains 581 alignments. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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