[Expression of Cyt C in brain of rats poisoned by tetramine]

Autor: Bin, Li, Wei-jia, Chen, Hong-tao, Yan, Jing-jie, Wu, Bo, Jin, Zhi-gang, Liao
Rok vydání: 2006
Předmět:
Zdroj: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 37(1)
ISSN: 1672-173X
Popis: To investigate the evidence for the judgement on legal cases of intoxication by tetramine.Fifty rats given tetramine by lavage were sacrificed at different time after intoxication. The expression of Cyt C was detected by immunohistochemistry, and the reasults were assessed by an image analysis system.There was a slight expression of Cyt C in control group. In intoxication group the expression of Cyt C increased after the rats were given tetramine for 30 minutes; it reached the peak at 24 hours after intoxication and kept up the level for 3 days, then it began to decrease and returned to the control level in 10 days.The regular change of Cyt C expression might be a useful sign for assessment in legal cases of intoxication by tetramine.
Databáze: OpenAIRE