The effect of time-of-flight and point spread function modeling on

Autor: Paul K R, Dasari, Judson P, Jones, Michael E, Casey, Yuanyuan, Liang, Vasken, Dilsizian, Mark F, Smith
Rok vydání: 2017
Předmět:
Zdroj: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. 25(5)
ISSN: 1532-6551
Popis: The effect of time-of-flight (TOF) and point spread function (PSF) modeling in image reconstruction has not been well studied for cardiac PET. This study assesses their separate and combined influence onThirty-six obese patients underwent rest-stressTOF improved polar map visual uniformity and increased septal wall perfusion by up to 10%. This increase was greater for larger patients, more evident for patients grouped by cross-sectional area than by BMI, and more prominent for females. PSF modeling increased perfusion by about 1.5% in all cardiac segments. TOF modeling generally decreased SRS and SSS with significant decreases between 2.4 and 3.0 (P .05), which could affect risk stratification; SDS remained about the same. With PSF modeling, SRS, SSS, and SDS were largely unchanged.TOF and PSF modeling affect regional and global perfusion, SRS, and SSS. Clinicians should consider these effects and gender-dependent differences when interpreting
Databáze: OpenAIRE