| Autor: |
L O, Frøholm, B P, Berdal, K, Bøvre, P, Gaustad, A, Harboe, E, Holten, E A, Høiby, A, Lystad, T, Omland, C E, Frasch |
| Rok vydání: |
1983 |
| Předmět: |
|
| Zdroj: |
NIPH annals. 6(2) |
| ISSN: |
0332-5652 |
| Popis: |
A combined serogroup B capsular polysaccharide and serotype 2a outer membrane complex meningococcal vaccine and a placebo preparation were tested double-blindly in 55 adult, male volunteers. The vaccine gave twofold increased binding antibodies, measured by ELISA, against non-capsular outer membrane antigen in 85 per cent of those vaccinated. Bactericidal antibodies towards a meningococcal serogroup C serotype 2a strain also increased fourfold or more among 85% vaccinated. New acquisition of meningococcal carriage was associated with antibody increase in one person from the placebo group. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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