4-Aminopyridine is a promising treatment option for patients with gain-of-function

Autor: Ulrike B S, Hedrich, Stephan, Lauxmann, Markus, Wolff, Matthis, Synofzik, Thomas, Bast, Adrian, Binelli, José M, Serratosa, Pedro, Martínez-Ulloa, Nicholas M, Allen, Mary D, King, Kathleen M, Gorman, Bruria Ben, Zeev, Michal, Tzadok, Lily, Wong-Kisiel, Dragan, Marjanovic, Guido, Rubboli, Sanjay M, Sisodiya, Florian, Lutz, Harshad Pannikkaveettil, Ashraf, Kirsten, Torge, Pu, Yan, Christian, Bosselmann, Niklas, Schwarz, Monika, Fudali, Holger, Lerche
Rok vydání: 2021
Předmět:
Zdroj: Science translational medicine. 13(609)
ISSN: 1946-6242
Popis: Developmental and epileptic encephalopathies are devastating disorders characterized by epilepsy, intellectual disability, and other neuropsychiatric symptoms, for which available treatments are largely ineffective. Following a precision medicine approach, we show for
Databáze: OpenAIRE