Lymphomas and leukemias in the relatives of patients with mycosis fungoides

Autor:	M H, Greene, H A, Pinto, J A, Kant, K, Siler, E C, Vonderheid, S I, Lamberg, N A, Dalager
Rok vydání:	1982
Předmět:	Adult Male Leukemia Adolescent Lymphoma Racial Groups Age Factors Middle Aged Hodgkin Disease United States Pedigree Mycosis Fungoides Sex Factors Humans Female Epidemiologic Methods Aged
Zdroj:	Cancer. 49(4)
ISSN:	0008-543X
Popis:	Of 526 consecutive patients with cutaneous T-cell lymphomas, 21 had first-degree relatives with lymphoproliferative or hematopoietic malignancies. Twenty-nine such tumors occurred in the 21 kindreds. Hodgkin's disease accounted for one-third of this total, with various leukemias (11 cases), non-Hodgkin's lymphoma (five cases), and multiple myeloma (three cases) comprising the remainder. These data suggest that genetically-determined immunoregulatory abnormalities may represent a shared pathway of oncogenesis in diverse lymphoproliferative and hematopoietic malignancies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::e260d6e82128648fce1fa6a0790c3991 https://pubmed.ncbi.nlm.nih.gov/7055783 Zobrazit plný text záznamu Plný text