Genetic factors involved in human G gamma and A gamma globin gene expression

Autor:	R, Bouhass, R, Taleb-Bendiab, J, Starck, F, Morle, M, Aguercif, J, Godet
Rok vydání:	1988
Předmět:	Genes Chromosomes Human Pair 11 Humans Thalassemia Anemia Sickle Cell Globins Pedigree
Zdroj:	European journal of haematology. 40(4)
ISSN:	0902-4441
Popis:	G gamma to A gamma globin ratios, haplotypes at the beta globin gene cluster and the C----T substitution at -158 5' to the G gamma globin gene were studied in three Algerian families that include SS or S-beta(0) thal patients. G gamma to A gamma ratios were found similar, within a family, in subjects displaying the same combination of chromosomes 11, the ratio observed for a given combination depending on the chromosome haplotypes. Our data can be explained by the existence of several alleles of a genetic factor closely linked to the beta globin gene cluster and involved in the determination of G gamma to A gamma globin ratio.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::e25a090697d83111265399e1ea53e262 https://pubmed.ncbi.nlm.nih.gov/3366225 Zobrazit plný text záznamu Plný text