| Autor: |
Kazimierz, Madaliński, Paulina, Godzik, Irena, Zimmermann-Górska, Mariusz, Puszczewicz, Katarzyna, Dzierzanowska-Fangrat, Joanna, Jabłońska, Jan, Zeromski |
| Rok vydání: |
2009 |
| Předmět: |
|
| Zdroj: |
Przeglad epidemiologiczny. 63(2) |
| ISSN: |
0033-2100 |
| Popis: |
The subject of study were 104 patients with the primary Sjögren Syndrome (p. Sj. s.) in whom markers of hepatitis C infection were investigated. All the patients fulfilled the criteria of the European Expert Group of the Sjögren Syndrome. Antibodies anti-HCV were found in 20 patients (19.2%) and HCV-RNA found in 5 patients (4.8%). These data were compared with those observed in several European countries and Japan. The following percentages of anti-HCV were observed until now in p.Sj.s. patients: Swedish--2%, Hungarian--6%, Japanese--12%, French--17%, Polish--19% and Spanish--26%. Our patients in whom liver data were available, showed only minor elevations of ALT and AST. International team of experts postulated the delineation of the disease entity: 'HCV-related primary Sjögren syndrome', separate from the p.Sj.s. itself. If this will be substantiated, we can put forward the hypotesis that 'HCV-related p.Sj.s.' may develop in a special subgroup of persons, perhaps genetically predisposed, and is a part of extrahepatic manifestations of HCV infection. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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