| Autor: |
Anas A, Mohamed, Zohour I, Nabil, Mohamed S, El-Naggar |
| Rok vydání: |
2022 |
| Zdroj: |
The journal of venomous animals and toxins including tropical diseases. 28 |
| ISSN: |
1678-9199 |
| Popis: |
A combination of pharmacological and biomedical assays was applied in this study to examine the bioactivity ofTwo doses (1/5 and 1/10 of LCThe tail immersion time was significantly increased in venom-treated mice compared with the control group. Also, a significant reduction in writhing movement was recorded after injection of both venom doses compared with the control group. In addition, only the high venom concentration has a mild anti-inflammatory effect at the late inflammation stage. The induced pyrexia was also decreased significantly after treatment with both venom doses. On the other hand, significant increases were observed in lipid peroxidation (after 4 hours) and reduced glutathione contents and glutathione peroxidase activity, while contents of lipid peroxidation and nitric oxide (after 24 hours) and catalase activity were depleted significantly after venom administration.These results indicated that the crude venom of |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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