| Autor: |
Liping, Luo, Wanxiang, Jiang, Hui, Liu, Jicheng, Bu, Ping, Tang, Chongyangzi, Du, Zhipeng, Xu, Hairong, Luo, Bilian, Liu, Bo, Xiao, Zhiguang, Zhou, Feng, Liu |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Journal of molecular endocrinology. 60(4) |
| ISSN: |
1479-6813 |
| Popis: |
The growth factor receptor bound protein GRB10 is an imprinted gene product and a key negative regulator of the insulin, IGF1 and mTORC1 signaling pathways. GRB10 is highly expressed in mouse fetal liver but almost completely silenced in adult mice, suggesting a potential detrimental role of this protein in adult liver function. Here we show that the |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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