[Clinical characteristics of patients with antisynthetase syndrome and positive anti-Ro52 antibody]

Autor: X, Zhang, X M, Zhao, Q H, Yang, C F, Lian, W, Li, L, Yang, J M, Lu, W J, Guan, L J, Zhang, S H, Cheng, H, Li, S Y, Liu
Rok vydání: 2022
Předmět:
Zdroj: Zhonghua nei ke za zhi. 61(2)
ISSN: 0578-1426
Popis: To analyze the clinical characteristics of patients with antisynthetase syndrome (ASS) and positive anti-Ro52 antibody. The clinical data of 203 ASS patients admitted to the First Affiliated Hospital of Zhengzhou University from 2017 to 2020 were analyzed retrospectively. Demographics, clinical manifestations, laboratory results, treatment and outcome were collected including data of 18 patients with rapidly progressive interstitial lung disease (RP-ILD). In total, the majority were women (148,72.9%). The average onset age was (51.9±13.3) years. There were 163 (80.3%) patients with positive anti-Ro52 antibody. The positivity in women (77.3% vs. 55.0%,分析抗Ro52抗体阳性的抗合成酶综合征(ASS)患者的临床特征。收集2017年至2020年郑州大学第一附属医院风湿免疫科和呼吸科住院确诊的203例ASS患者,回顾性分析其一般资料、临床表现、实验室检查等。203例ASS患者中男55例,女148例,ASS发病年龄(51.9±13.3)岁。抗Ro52抗体阳性者163例,抗Ro52抗体阴性者40例。与抗Ro52抗体阴性者比,抗Ro52抗体阳性者中女性多见[77.3%(126/163)比 55.0%(22/40),
Databáze: OpenAIRE