PhOxi-Seq: Single-Nucleotide Resolution Sequencing of

Autor: Kimberley, Chung Kim Chung, Yasaman, Mahdavi-Amiri, Christopher, Korfmann, Ryan, Hili
Rok vydání: 2022
Předmět:
Zdroj: Journal of the American Chemical Society. 144(13)
ISSN: 1520-5126
Popis: Chemical modifications regulate the fate and function of cellular RNAs. Newly developed sequencing methods have allowed a deeper understanding of the biological role of RNA modifications; however, the vast majority of post-transcriptional modifications lack a well-defined sequencing method. Here, we report a photo-oxidative sequencing (PhOxi-seq) approach for guanosine
Databáze: OpenAIRE