The role of subchondral bone, and its histomorphology, on the dynamic viscoelasticity of cartilage, bone and osteochondral cores

Autor: N L A, Fell, B M, Lawless, S C, Cox, M E, Cooke, N M, Eisenstein, D E T, Shepherd, D M, Espino
Rok vydání: 2018
Předmět:
Zdroj: Osteoarthritis and Cartilage
ISSN: 1522-9653
Popis: Summary Objective Viscoelastic properties of articular cartilage have been characterised at physiological frequencies. However, studies investigating the interaction between cartilage and subchondral bone and the influence of underlying bone histomorphometry on the viscoelasticity of cartilage are lacking. Method Dynamic Mechanical Analysis (DMA) has been used to quantify the dynamic viscoelasticity of bovine tibial plateau osteochondral cores, over a frequency sweep from 1 to 88 Hz. Specimens (approximately aged between 18 and 30 months) were neither osteoarthritic nor otherwise compromised. A maximum nominal stress of 1.7 MPa was induced. Viscoelastic properties of cores have been compared with that of its components (cartilage and bone) in terms of the elastic and viscous components of both structural stiffness and material modulus. Micro-computed tomography scans were used to quantify the histomorphological properties of the subchondral bone. Results Opposing frequency-dependent loss stiffness, and modulus, trends were witnessed for osteochondral tissues: for cartilage it increased logarithmically (P 0.05). A linear relationship between the subchondral bone plate (SBP) thickness and cartilage thickness (P
Databáze: OpenAIRE