| Autor: |
C, Berger, D, Frappaz, E, Bouffet, H, Sobol, C, Charra, T, Philip, M, Brunat-Mentigny, M F, Bertheas |
| Jazyk: |
francouzština |
| Rok vydání: |
1994 |
| Předmět: |
|
| Zdroj: |
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie. 1(6) |
| ISSN: |
0929-693X |
| Popis: |
The relationship between constitutional chromosome aberrations and a predisposition to malignancy has already been established.A 4 year-old boy was admitted suffering from abdominal mass. Biopsies of the tumor and bone marrow showed a stage IV Burkitt's lymphoma. Karyotype showed a constitutional t(1;6)(p36;q22) in initial bone marrow samples and peripheral lymphocytes. No classic Burkitt's type translocation was demonstrated in the malignant bone marrow cells.Our case is similar to four other reported cases. The break-points 1p36 and 6q22 seem to be involved in several malignant tumors, especially lymphomas. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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