| Autor: |
Iu M, Lopukhin, I P, Andrianova, V E, Ryzhenkov, N A, Samoĭlova, A M, Chistiakova, Iu V, Frolova, I A, Iamskov, V I, Sergienko, Ia I, Lapuk |
| Rok vydání: |
1994 |
| Předmět: |
|
| Zdroj: |
Voprosy meditsinskoi khimii. 40(1) |
| ISSN: |
0042-8809 |
| Popis: |
Hypolipidemic properties of the synthesized enterosorbent, water soluble polymer containing covalently immobilized trimethylamine ethanol chloride, were studied. Content of cholesterol in blood was decreased by 29% and accumulation of cholesterol in liver tissue--by 22% after oral administration of the enterosorbent at a dose of 250 mg/kg into rats with hypercholesterolemia. Cholestyramine exhibited the similar effect only at a dose of 2.5 g/kg. Except for the hypocholesterolemic effect, the enterosorbent altered also the lipoprotein spectrum in rat blood serum. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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