[Fish oils and rheumatoid arthritis. A randomized and double-blind study]

Autor: K L, Faarvang, G L, Nielsen, B S, Thomsen, K L, Teglbjaerg, T M, Hansen, H H, Lervang, E B, Schmidt, J, Dyerberg, E, Ernst
Rok vydání: 1994
Předmět:
Zdroj: Ugeskrift for laeger. 156(23)
ISSN: 0041-5782
Popis: The effect of dietary supplementation with n-3 polyunsaturated fatty acids (n-3 PUFA) on disease variables in patients with active rheumatoid arthritis was evaluated in a multicentre, randomized and double blind study. Fifty-one patients with active rheumatoid arthritis were included from three Danish hospital Departments of Rheumatology. The patients were allocated to 12 weeks of treatment with either six n-3 PUFA capsules (3.6 g) or six capsules with a fat composition averaging the Danish diet. Small but significant improvements in morning stiffness, joint tenderness and C-reactive protein were observed. There were no serious side-effects. Dietary supplementation with n-3 PUFA in patients with active rheumatoid arthritis has a modest effect on three out of eight disease variables, without effect on other traditional parameters for monitoring disease activity.
Databáze: OpenAIRE