| Autor: |
Sony, Tuteja, Henry, Glick, William, Matthai, Irving, Nachamkin, Ashwin, Nathan, Karen, Monono, Craig, Carcuffe, Karen, Maslowski, Gene, Chang, Taisei, Kobayashi, Saif, Anwaruddin, John, Hirshfeld, Robert L, Wilensky, Howard C, Herrmann, Daniel M, Kolansky, Daniel J, Rader, Jay, Giri |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Circulation. Genomic and precision medicine. 13(1) |
| ISSN: |
2574-8300 |
| Popis: |
At the time of percutaneous coronary intervention, participants were randomly assigned to prospective rapid point-of-care genotyping ofA total of 504 participants were randomized, 249 to the genotyped and 255 to the usual care group. The participants were primarily men (73%); age, 63±10 years; and 50% had acute coronary syndromes. In the genotyped group, 28% were carriers of loss-of-function alleles (*2, *3). The use of prasugrel or ticagrelor was significantly higher in the genotyped group compared with the usual care group (30% versus 21%; odds ratio, 1.60 [95% CI, 1.07-2.42];In a randomized controlled trial of clinicalURL: http://www.clinicaltrials.gov. Unique Identifier: NCT02508116. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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