Clinical value of the Integrated Pulmonary Index

Autor: Andrea, Riphaus, Till, Wehrmann, Tim, Kronshage, Christoph, Geist, Christian P, Pox, Stefan, Heringlake, Wolff, Schmiegel, Analena, Beitz, Alexander, Meining, Michaela, Müller, Stefan, von Delius
Rok vydání: 2016
Předmět:
Zdroj: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 49(1)
ISSN: 1878-3562
Popis: The Integrated Pulmonary Index170 patients with standard monitoring randomly underwent either a blinded recording of capnography (control group, n=87) or capnography, including automated IPI calculation (IPI group, n=83), during deep sedation with midazolam and propofol. The primary endpoint was the maximum decrease of oxygen saturation from the baseline level before sedation. Secondary endpoints: incidence of hypoxemia (SaOMean propofol dose in the IPI group (245±61mg) was comparable to the control group (225±47mg). The average drop of the oxygen saturation in the IPI group (6.5±4.1%) was nearly identical to that of the control group (7.1±4.6%, p=0.44). Apnea episodes15s was found in 46 patients of the control and 31 of the IPI group (p0.05). Frequency of occurrence of a drop in pOA clinically appealing advantage of IPI-assessment during deep sedation with midazolam and propofol for interventional endoscopy could not be documented. However, IPI registration was more effective in reducing the incidence of apnea episodes.
Databáze: OpenAIRE